痛風的發生是因體內的普林代謝異常導致高尿酸血症，而使尿酸鈉鹽沈積在關節腔內，造成關節發炎腫脹，少數嚴重者可造成變形，下列各項知識將有助於自我照顧、控制病情。
1.藥物方面按時且正確遵照醫囑服用降低尿酸藥物，對藥物的預期效果和副作用有不明白處，請返院門診。如僅為高尿酸血症，無合併其他疾病，且無痛風關節炎發作者，則不需服用降尿酸藥物。
2.在活動與運動方面
2.1.急性期腫脹痛風之關節宜多休息。
2.2.慢性關節破壞者，則宜注意關節活動，避免關節攣縮與變形。
3.急性期關節紅痛時先給予冰敷，一天三至四次，每次十五分鐘。用熱敷時機，請依醫師指示。
4.在飲食方面
4.1.肥胖者須減輕體重，以減輕關節負荷。
4.2.儘量多喝水，每日至少2,000cc，儘量避免喝酒。
4.3.避免攝取過多的蛋白質，減少攝取含普林量高的食物。
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